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期刊名称: Trends in Neurosciences
Volume:35    Issue:9        Page:527-535
ISSN:0166-2236

Functional network dysfunction in anxiety and anxiety disorders期刊论文

作者: Sylvester C.M Corbetta M Raichle M.E Rodebaugh T.L Schlaggar B.L
DOI:10.1016/j.tins.2012.04.012

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页码: 527-535
被引频次: 188
出版者: Elsevier Ltd,ELSEVIER SCIENCE LONDON,Elsevier Science Publishers
期刊名称: Trends in Neurosciences
ISSN: 0166-2236
卷期: Volume:35    Issue:9
语言: English
摘要: A recent paradigm shift in systems neuroscience is the division of the human brain into functional networks. Functional networks are collections of brain regions with strongly correlated activity both at rest and during cognitive tasks, and each network is believed to implement a different aspect of cognition. We propose here that anxiety disorders and high trait anxiety are associated with a particular pattern of functional network dysfunction: increased functioning of the cingulo-opercular and ventral attention networks as well as decreased functioning of the fronto-parietal and default mode networks. This functional network model can be used to differentiate the pathology of anxiety disorders from other psychiatric illnesses such as major depression and provides targets for novel treatment strategies.
相关主题: Neurology, anxiety, fMRI, anxiety disorder, brain network, functional network, Anxiety, Brain network, FMRI, Functional network, Anxiety disorder, DEFAULT MODE NETWORK, ANTERIOR CINGULATE ACTIVATION, ATTENTIONAL BIAS, NEUROSCIENCES, SOCIAL PHOBIA, COGNITIVE-CONTROL, TRAIT ANXIETY, EVENT-RELATED POTENTIALS, EMOTION REGULATION, MEDIAL PREFRONTAL CORTEX, ANGRY FACES, Brain - physiopathology, Humans, Anxiety - physiopathology, Models, Neurological, Nerve Net - physiopathology, Anxiety Disorders - physiopathology, Brain Diseases - physiopathology, Neurosciences, Analysis, Index Medicus, Anxiety Disorder, Functional Network, Brain Network,

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