A new symmetrical dihydrazide derivative organogelator (MBH-10) with two dihydrazide units was synthesized. The gelation property and the self-assembly behavior were researched by FE-SEM, XRD, rheology, FT-IR, concentration-dependent 1 H NMR, etc. Gels could be formed in acetonitrile and n-octanol with good mechanical properties. Quadruple hydrogen bonds between the dihydrazide units were viewed as the main driving force in the self-assembly process. The MBH-10 gelator which showed both anion-response (F − , H 2 PO 4 − ) property and relatively green, efficient toxic dyes removal property might be used in the field of anion sensing and environment remediation in the future.