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期刊名称: High Altitude Medicine & Biology
Volume:17    Issue:2        Page:61-69
ISSN:1527-0297

Chronic Mountain Sickness: Clinical Aspects, Etiology, Management, and Treatment期刊论文

作者: Villafuerte Francisco C Corante Noemí
DOI:10.1089/ham.2016.0031

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页码: 61-69
被引频次: 19
出版者: Mary Ann Liebert, Inc,MARY ANN LIEBERT, INC
期刊名称: High Altitude Medicine & Biology
ISSN: 1527-0297
卷期: Volume:17    Issue:2
语言: English
摘要: Villafuerte, Francisco C., and Noemí Corante. Chronic mountain sickness: clinical aspects, etiology, management, and treatment. High Alt Med Biol. 17:61–69, 2016.—Millions of people worldwide live at a high altitude, and a significant number are at risk of developing Chronic Mountain Sickness (CMS), a progressive incapacitating syndrome caused by lifelong exposure to hypoxia. CMS is characterized by severe symptomatic excessive erythrocytosis (EE; Hb ≥19 g/dL for women and Hb ≥21 g/dL for men) and accentuated hypoxemia, which are frequently associated with pulmonary hypertension. In advanced cases, the condition may evolve to cor pulmonale and congestive heart failure. Current knowledge indicates a genetic predisposition to develop CMS. However, there are important risk factors and comorbidities that may trigger and aggravate the condition. Thus, appropriate medical information on CMS is necessary to provide adequate diagnosis and healthcare to high-altitude inhabitants. After reviewing basic clinical aspects of CMS, including its definition, diagnosis, and common clinical findings, we discuss aspects of its etiology, and address its epidemiology, risk factors, and treatment.
相关主题: Clinician's Corner, SPORT SCIENCES, high altitude, PULMONARY-HYPERTENSION, GLUCOSE-INTOLERANCE, HYPOXEMIA, STRONG ASSOCIATION, excessive erythrocytosis, PATHOPHYSIOLOGY, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH, chronic hypoxia, LIPID PROFILE, BIOPHYSICS, chronic mountain sickness, MONGES-DISEASE, HIGH-ALTITUDE POLYCYTHEMIA, HIGHLANDERS, Genetic Predisposition to Disease, Humans, Hypoxia - etiology, Risk Factors, Male, Polycythemia - etiology, Altitude Sickness - etiology, Altitude Sickness - therapy, Female, Disease Management, Altitude Sickness - pathology, Chronic Disease, Hypertension, Pulmonary - etiology, Altitude,

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