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期刊名称: Trends in Biotechnology
Volume:15    Issue:5        Page:185-192
ISSN:0167-7799

Bacterial surface display: trends and progress期刊论文

作者: Ståhl Stefan Uhlén Mathias
DOI:10.1016/S0167-7799(97)01034-2

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页码: 185-192
被引频次: 144
出版者: Elsevier Ltd,ELSEVIER SCIENCE LONDON
期刊名称: Trends in Biotechnology
ISSN: 0167-7799
卷期: Volume:15    Issue:5
语言: English
摘要: Heterologous surface display on Gram-negative bacteria was first described a decade ago and is now an active research area. More recently, strategies for surface display on Gram-positive bacteria have also been devised and these carry some inherent advantages. Bacterial surface display has found a range of applications in the expression of various antigenic determinants, heterologous enzymes, single-chain antibodies, polyhistidyl tags and even entire peptide libraries. This article explains the basis of bacterial surface display and discusses current uses and possible future trends of this emerging technology.
相关主题: GRAM-POSITIVE BACTERIA, OUTER-MEMBRANE, STREPTOCOCCUS-GORDONII, PROTEIN-A, EXTERNAL SURFACE, BIOTECHNOLOGY & APPLIED MICROBIOLOGY, RECOMBINANT PROTEINS, ESCHERICHIA-COLI K-12, SALMONELLA-TYPHIMURIUM, CELL-SURFACE, STAPHYLOCOCCUS-AUREUS, Recombinant Proteins - metabolism, Biotechnology, Bacteria - metabolism, Epitopes - metabolism, Cell Membrane - genetics, Recombinant Proteins - genetics, Gram-Negative Bacteria - metabolism, Epitopes - genetics, Bacteria - genetics, Bacterial Vaccines - isolation & purification, Immunoglobulin Fragments - metabolism, Vaccines, Synthetic - isolation & purification, Gram-Positive Bacteria - genetics, Gram-Positive Bacteria - metabolism, Enzymes - genetics, Immunoglobulin Fragments - genetics, Cell Membrane - metabolism, Gram-Negative Bacteria - genetics, Enzymes - metabolism,

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